'I was born twice: first; as a baby girl; on a remarkably smogless Detroit day of January 1960; and then again; as a teenage boy; in an emergency room near Petoskey; Michigan; in August of l974.' So begins the breathtaking story of Calliope Stephanides and her truly unique family secret; born on the slopes of Mount Olympus and passed on through three generations. Growing up in 70s Michigan; Calliope's special inheritance will turn her into Cal; the narrator of this intersex; inter-generational epic of immigrant life in 20th century America. Middlesex won the 2003 Pulitzer Prize for Fiction.